Jadassohn-Lewandowski Syndrome: This syndrome is a form of what is called elephant nails from birth (pachyonychia congenita).
The characteristic features include:
Generation after generation in a family may show the syndrome. It is an autosomal dominant trait. The gene responsible for the syndrome is on chromosome 12 (in band 12q13) and a single copy of the gene (named PD1) is capable of causing the disease. The basic abnormality is a mutation (change) in a gene for keratin, a primary constituent of nails, hair, and skin. Alternate names for the syndrome include pachyonychia congenita of the Jadassohn-Lewandowski type and pachyonychia congenita with natal teeth and type 1 pachyonychia congenita. The syndrome is named for the professor of dermatology at the University of Bern in Switzerland, Josef Jadassohn (1860-1936), and his colleague, Felix Lewandowski (1879- 1921), who first described the syndrome in 1906. About their patient, a 15-year-old girl, they wrote: "The nail plates of all the fingers and toes are extremely thickened, and so hard that they cannot be cut with a scissors; the father has to trim them with a hammer and chisel."
Jadassohn-Lewandowski syndrome information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues.
Jadassohn-Lewandowski Syndrome: This syndrome is a form of what is called elephant nails from birth (pachyonychia congenita). The characteristic features include:
Definition of Jadassohn-Lewandowski syndrome. Provided by Stedman's medical dictionary and Drugs.com. Includes medical terms and definitions.
Jadassohn-Lewandowski Syndrome Definition at Online Medical Dictionary. Now you can find here difficult medical language medical terms in easy-to-understand explanations.
Jadassohn-Lewandowski Syndrome, medical definition, medical terms, Online Medical Dictionary and glossary with medical definitions